Probiotics can help to improve the affect of periodontal disease and more in a double-blind survey. The placebo-controlled study found that the probiotic Lactobacillus of standard treatment for chronic periodontitis scouting replanning by 53% according to the article. By the end of the 12 week-long study 53% fewer sites on teeth and patients with deep dental pockets and supplemented by the above work in need of surgery compared with with the placebo group after the intervention period.

It was also concluded that 67% of patients in the placebo group at into the high risk category of disease progression on a corresponding figure for patients treated by the probiotic was only 27%.

It can therefore be concluded that probiotics have a major influence activity of hundreds of genes helping to express in a positive disease fighting manner effects in periodontal disease .